Cell Biology, Physiology, and Metabolism - CPM


CPM at Penn includes an interdisciplinary group of investigators with a common interest in understanding the inner workings of the basic unit of life, the cell. Major research themes include:

  • Signal Transduction

  • Intracellular Trafficking and Organelle Function

  • Membrane Transport

  • Cytoskeleton, Motility, and Adhesion

  • Metabolism

Researchers at Penn employ a broad array of organisms, from yeasts to human, and state-of-the-art research tools - microscopy, genomic and proteomic technologies, metabolomics, electrophysiology, biochemistry and molecular biology.

We strive to foster diverse interdisciplinary research collaborations between traditional cell biology labs and colleagues investigating the molecular foundations of human disease, embryonic development, biomedical engineering, and structural biology. In particular, we leverage our unique access to a large academic integrated medical center, the Penn School of Medicine, to connect fundamental question in cell biology to human disease. We have close relationships with a number of Institutes at Penn, including the Penn Muscle Institute (PMI), the Cardiovascular Institute (CVI), and the Institute for Diabetes Obesity and Metabolism (IDOM). We strive to provide a stimulating and challenging environment for the training of students and postdoctoral fellows in cutting edge cell biology research.


Research Areas


Cell Signaling


Cellular Trafficking & Organelle Function

Bi lab-Artwork-Oct20-2020.png

Membrane Transport


Cytoskeleton, Motility, & Adhesion

Lee.EddieLab_NFTs pseudocolor.tif




Microscopy Outreach.jpg

December 7 , 2020

The CPM Diversity Committee held a virtual microscopy lesson for students at the Philadelphia High School for Girls.

Read more here.



Graduate Education

CPM faculty primarily mentor graduate students from programs in the Biomedical Graduate Studies (BGS) umbrella group, but frequently advise students in other biology-related departments on the Penn Campus.  

Prospective students that are interested in the CPM graduate program should apply to the Cell and Molecular Biology (CAMB) program and select CPM as the sub-program. 

Postdoctoral Training
Please contact individual faculty members to learn about post-doctoral training opportunities.


Penn Cell Biology, Physiology, and Metabolism

Perelman School of Medicine at the University of Pennsylvania

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