Yale Goldman, MD, PhD
Department of Physiology
615-620 Clinical Research Building
The Goldman lab develops novel biophysical tools, single molecule fluorescence microscopy and optical traps to investigate structural dynamics of biological machines. Protein synthesis on the ribosome, molecular motors that power intracellular cargo trafficking, heart and skeletal muscles and AAA ring domain proteins are our main targets. Alleviating diseases such as Duchenne muscular dystrophy, cystic fibrosis and cardiac myopathies are long term benefits of this fundamental research.